Carcinoid Heart Disease: Starting From Heart Failure

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Carcinoid Heart Disease: Starting From Heart Failure

Carcinoid syndrome is the constellation of symptoms mediated by humoral factors produced by some carcinoid tumors. It consists primarily of vasomotor symptoms, gastrointestinal hypermotility, hypotension, and bronchospasm, due to the production and release of vasoactive substances. Carcinoid heart disease occurs in more than 50% of patients with carcinoid syndrome; in some cases, it represents ...

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Carcinoid heart disease.

The patient, C.P., is a 59-year-old woman who was diagnosed with metastatic carcinoid of the terminal ileum in May 2003. In June 2003, she underwent an extensive resection including hemicolectomy, cholecystectomy, distal pancreatectomy, and splenectomy with metastatic disease in her pancreas, mesentery, and liver. She had been treated with octreotide, everolimus, oxaliplatin, and multiple hepat...

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Carcinoid heart disease.

Carcinoid tumors are relatively rare neuroendocrine malignancies most commonly originating from enterochromaffin cells in the gastrointestinal tract. The incidence is 1 in 100 000 of the general population.1 They usually grow slowly over years, commonly causing no symptoms at all until they become large or have metastasized. Carcinoid tumors of midgut origin may secrete large amounts of vasoact...

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Carcinoid heart disease.

comes and angiotensin converting enzyme inhibitor effects in patients with predominantly left ventricular dysfunction and heart failure. Eur J Heart Fail 2014;16:325–333. 24. Eklind-Cervenka M, Benson L, Dahlstrom U, Edner M, Rosenqvist M, Lund LH. Association of candesartan vs. losartan with all-cause mortality in patients with heart failure. JAMA 2011;305:175–182. 25. Lauer MS, D’Agostino RB ...

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Carcinoid Heart Disease

THE CARCINOID TUMOR is a slow growing malignant lesion capable of distant metastases. Frequently, patients afflicted with this tumor develop a pathognomonic fibrosis of valves and endocardium involving primarily the right side of the heart. Although only 50% of the patients with metastatic disease survive for 3 years, these patients usually succumb from intractable congestive heart failure.' Re...

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ژورنال

عنوان ژورنال: Journal of Investigative Medicine High Impact Case Reports

سال: 2017

ISSN: 2324-7096,2324-7096

DOI: 10.1177/2324709617713511